The current clinical standard of the Diagnostic and Statistical Manual of mental disorders (DSM-5), post-traumatic stress disorder (PTSD) may develop after an individual has been through an experience that is life-threatening or posed the potential of serious bodily harm to self, or others. The main impact of these symptoms comes from the fact that they persist into an individual's life, overwhelming their ability to maintain healthy physiological and emotional equilibrium. When an individual is unable to overcome the acute stress response symptoms of fear, dread, anxiety, intrusive memories and/or dreams of the trauma, the chronic condition that characterizes post-traumatic stress ensues. PTSD symptoms are often precipitated by financial stress, marital discord, natural disasters, automobile accidents, personal or terrorist attacks, sexual violence, or combat exposure, among others.

The neurological and physiological nature of PTSD symptoms can have dire consequences on one's physical and mental health. The disruption of the endocrine and nervous systems, such as the chronic activation of the sympathetic fight-or-flight response, have been clinically associated with many other health conditions.